2002 V8 LSE here with 130k miles. Bought her new with about 8 miles on her in 12/2002.
Usual culprits: Coils, alternator, sway bar bushings, drivers side heated seat pad. All original window regulators except drivers side. Only had to replace that one due to break in via pried window. Ball joints , tie rods, and all other suspension bushings still original and still in fine condition. Replaced my shocks all around at about 60k when I had the Eibach springs installed. The steering/suspension is probably whats amazing me the most as its troublefree and well put together with no corners cut, in my opinion.
Had my tranny fluid flushed at around 75k just because. Change my own oil with WalMarts brand of full synthetic and fram filters every 10k miles. I had originally planned to keep this car for 8 years (meaning Id be selling it now) but based on how well everything (including interior materials and paint, etc) is holding up and how great she looks (I literally have NO dings or scratches in the paint at all) I plan to now hold on to her for at least two more years. That will allow me to continue paying into my savings account my old car payment that I used to pay..and pay cash for the next replacement for the LS.
Right now Im thinking my replacement will be a used CLS class Benz