Over a long time, yes.
How much time?
I put well over 350K on my 95 with a 255 pump.
the "volume of the pump" should have no bearing on the pressure regulator, it's just a pressure relief valve.
pretty simple stuff.
I think most people have an ordinary FPR failure and incorrectly "blame" the pump.
that's my story and I'm stickin to it.