It can work but you will have to shave the inner fender.
I have custom wheels on my LS, 20x9.5 on 285-30's with a custom offset of 57.15mm and mine fit without shaving inner fender. So with a 48mm offset, those wheels will push further outward from mine by .36".
So yeah it should fit if shaved, use 275 tires, it would be a nice aggressive look which would give it a great stance.
Now I would not try that for the fronts.